Sp-ATPαS
Sp-ATPαS is a regulator of ATP-binding proteins. Sp-ATPαS is a competitive antagonist of the human P2Y1 receptor, which can inhibit the calcium signal induced by ADP. Sp-ATPαS is metabolically more stable than ATP[1]. Sp-ATPαS can be used to study the binding patterns of metals and nucleotides in enzymatic reactions.
Product Specifications
CAS Number
58976-48-0
UNSPSC
12352005
Target
P2Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sp-atpαs.html
Smiles
O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O[C@@H]1CO[P@@](OP(OP(O)(O)=O)(O)=O)(S)=O
Molecular Formula
C10H16N5O12P3S
Molecular Weight
523.25
References & Citations
[1]Connolly BA, Eckstein F. S-Methylated nucleoside phosphorothioates as probes of enzyme metal X nucleotide binding sites. Biochemistry. 1982 Nov 23;21 (24) :6158-67. |[2]Léon C, et al. The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells. FEBS Lett. 1997 Feb 10;403 (1) :26-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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