PD 118440
PD 118440 is an orally active dopamine (DA) agonist. PD 118440 has significant central nervous system effects, including inhibition of striatal DA synthesis, suppression of DA neuron firing, and reversal of Reserpine -induced depression in rats[1].
Product Specifications
CAS Number
108351-90-2
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pd-118440.html
Smiles
NC1=NC(C2=CCCN(C2)CCC)=CS1
Molecular Formula
C11H17N3S
Molecular Weight
223.34
References & Citations
[1]Jaen J C, et al. 4- (1, 2, 5, 6-Tetrahydro-1-alkyl-3-pyridinyl) -2-thiazolamines: a novel class of compounds with central dopamine agonist properties[J]. Journal of medicinal chemistry, 1990, 33 (1) : 311-317.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC740225-100 1x 100 µL
Major Vault Protein (MVP) (1032), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470012-100 1x 100 µL
Tyrosinase (T311), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680806-100 1x 100 µL
TYRP1 (Tyrosinase Related Protein 1) (TA99), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC471791-500 1x 500 µL
SOX2 (Transcription Factor) (SOX2/1791), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040497-100 1x 100 µL
PAX7 (PAX7/497), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details