Ritobegron (hydrochloride)
Ritobegron, a prodrug of the active compound, KUC-7322, is a selective β3 -adrenoceptor agonist. Ritobegron decreases intravesical pressure with minimal effects on the cardiovascular system.
Product Specifications
CAS Number
476333-91-2
Product Name Alternative
KUC-7483 (hydrochloride)
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Endocrinology; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ritobegron-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
CCOC(COC1=C(C=C(C(C)=C1)CCN[C@@H](C)[C@@H](C2=CC=C(C=C2)O)O)C)=O.Cl
Molecular Formula
C23H32ClNO5
Molecular Weight
437.96
References & Citations
[1]Maruyama I, Goi Y, Tatemichi S, et al. Bladder selectivity of the novel β₃-agonist ritobegron (KUC-7483) explored by in vitro and in vivo studies in the rat. Naunyn Schmiedebergs Arch Pharmacol. 2012;385 (8) :845-852. |[2]Maruyama I, Tatemichi S, Goi Y, et al. Effects of ritobegron (KUC-7483), a novel selective β3-adrenoceptor agonist, on bladder function in cynomolgus monkey. J Pharmacol Exp Ther. 2012;342 (1) :163-168.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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