8-NBD-cGMP
8-NBD-cGMP is a fluorescent analog of cyclic guanosine monophosphate and a potent, membrane-permeable, fluorescent activator of cGMP-dependent protein kinase isozymes I α and I β. 8-NBD-cGMP is barely fluorescent in aqueous solution but fluoresces strongly in hydrophobic environments such as hydrophobic protein binding sites[1]
Product Specifications
CAS Number
115993-88-9
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/8-nbd-cgmp.html
Smiles
O=C1C(N=C(SCCNC2=CC=C([N+]([O-])=O)C3=NON=C32)N4[C@H]5[C@H](O)[C@H](O6)[C@@H](COP6(O)=O)O5)=C4N=C(N)N1
Molecular Formula
C18H18N9O10PS
Molecular Weight
583.43
References & Citations
[1]Schmidpeter, et al. Ligand binding and activation properties of the purified bacterial cyclic nucleotide–gated channel SthK. Journal of General Physiology 150.6 (2018) : 821-834.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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