HSD17B13-IN-95
HSD17B13-IN-95 (1) is an inhibitor of 17 β-hydroxysteroid dehydrogenase (HSD17B13), and its IC50 value for estradiol is [1].
Product Specifications
CAS Number
[2849338-41-4]
UNSPSC
12352005
Target
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hsd17b13-in-95.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(C(NC2=C3C(N=CN(CCC4=CC=CC=C4OC(F)(F)F)C3=O)=CC=C2)=O)N=C1C(F)(F)F
Molecular Formula
C24H16F6N4O4
Molecular Weight
538.40
References & Citations
[1]Joshua Odingo, et al. Hydroxypyridine hsd17b13 inhibitors and uses thereof. 2019 Apr;15 (4) :322-330. WO2022216626A1.2022-10-13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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