(Rac) -D3S-001
(Rac) -D3S-001 is the racemate of D3S-001[2].
Product Specifications
CAS Number
2706637-43-4
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rac-d3s-001.html
Smiles
FC(F)(F)C(C(C)=CC(N)=C1F)=C1C2CC3=NC(OC[C@@]45N(CCC5)C[C@@H](C4)F)=NC(N6C[C@@H](N(CC6)C(C(F)=C)=O)CC#N)=C3CO2
Molecular Formula
C32H35F6N7O3
Molecular Weight
679.66
References & Citations
[1]Zhang J, et al. D3S-001, a KRAS G12C inhibitor with rapid target engagement kinetics, overcomes nucleotide cycling and demonstrates robust preclinical and clinical activities. Cancer Discov. 2024 May 8.|[2]Zhang yang, et al.Pyrimidoheterocyclic compounds and application thereof. Patent. WO2021180181
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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