Fosfenopril
Fosfenopril (Fosinoprilat) is a potent angiotensin converting enzyme (ACE) inhibitor. Fosfenopril alleviates lipopolysaccharide (LPS) -induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes[1][2].
Product Specifications
CAS Number
95399-71-6
Product Name Alternative
Fosinoprilat; Fosinoprilic acid; SQ 27519
UNSPSC
12352005
Hazard Statement
H360
Target
Angiotensin-converting Enzyme (ACE) ; Interleukin Related; NF-κB; TNF Receptor; Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/fosfenopril.html
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=P(CCCCC1=CC=CC=C1)(O)CC(N2C[C@H](C3CCCCC3)C[C@H]2C(O)=O)=O
Molecular Formula
C23H34NO5P
Molecular Weight
435.49
Precautions
H360
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
IL-1; IL-6; NF-κB; TLR4; TNFRSF5/CD40
Available Sizes
Frequently Asked Questions
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