Isoforskolin (Standard)
Product Specifications
UNSPSC Description
Isoforskolin (Standard) is the analytical standard of Isoforskolin. This product is intended for research and analytical applications. Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis[1].
Target Antigen
Interleukin Related; TNF Receptor
Type
Reference Standards
Related Pathways
Apoptosis;Immunology/Inflammation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/isoforskolin-standard.html
Smiles
C[C@@]12[C@@]3([C@@]([C@@H](O)[C@@H](OC(C)=O)[C@@]1([H])C(C)(CC[C@@H]2O)C)(O[C@](C=C)(C)CC3=O)C)O
Molecular Weight
410.50
References & Citations
[1]Zhao H, et al. Isoforskolin downregulates proinflammatory responses induced by <i>Borrelia burgdorferi</i> basic membrane protein A.Exp Ther Med. 2017 Dec;14(6):5974-5980.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N6927R/Isoforskolin-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N6927R/
CAS Number
64657-21-2
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