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Isoforskolin (Standard)

Product Specifications

UNSPSC Description

Isoforskolin (Standard) is the analytical standard of Isoforskolin. This product is intended for research and analytical applications. Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis[1].

Target Antigen

Interleukin Related; TNF Receptor

Type

Reference Standards

Related Pathways

Apoptosis;Immunology/Inflammation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/isoforskolin-standard.html

Smiles

C[C@@]12[C@@]3([C@@]([C@@H](O)[C@@H](OC(C)=O)[C@@]1([H])C(C)(CC[C@@H]2O)C)(O[C@](C=C)(C)CC3=O)C)O

Molecular Weight

410.50

References & Citations

[1]Zhao H, et al. Isoforskolin downregulates proinflammatory responses induced by <i>Borrelia burgdorferi</i> basic membrane protein A.Exp Ther Med. 2017 Dec;14(6):5974-5980.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N6927R/Isoforskolin-Standard-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N6927R/

CAS Number

64657-21-2

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