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Phospho-NDRG1 (T346) Recombinant Rabbit Monoclonal Antibody [PSH07-17]

Protein NDRG1 is a protein that in humans is encoded by the NDRG1 gene. This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. Mutations in this gene have been reported to be causative the autosomal-recessive version of Charcot-Marie-Tooth disease known as CMT4D. It has been reported that NDRG1 localizes to the endosomes and is a Rab4a effector involved in vesicular recycling.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

42 kDa antibody Anti GC4 antibody cap43 antibody cmt4d antibody Differentiation related gene1 protein antibody Differentiation-related gene 1 protein antibody Drg 1 antibody DRG-1 antibody drg1 antibody gc4 antibody GC4 antibody antibody hmsnl antibody Human mRNA for RTP complete cds antibody N myc downstream regulated gene 1 antibody N myc downstream regulated gene 1 protein antibody N-myc downstream-regulated gene 1 protein antibody Ndr 1 antibody ndr1 antibody NDRG 1 antibody Ndrg1 antibody NDRG1 protein antibody NDRG1_HUMAN antibody Nickel specific induction protein antibody Nickel specific induction protein Cap43 antibody Nickel-specific induction protein Cap43 antibody nmsl antibody Nmyc downstream regulated antibody Nmyc downstream regulated gene1 antibody Nmyc downstream regulated gene1 protein antibody Protein NDRG1 antibody Protein regulated by oxygen 1 antibody Protein regulated by oxygen1 antibody Proxy1 antibody Reduced in tumor antibody Reducin antibody Reducing agents and tunicamycin responsive protein antibody Reducing agents and tunicamycin-responsive protein antibody Rit42 antibody RTP antibody targ1 antibody TDD5 antibody tdds antibody Tunicamycin responsive protein antibody

Abbreviation

NDRG1, CAP43, DRG1, RTP

Swiss Prot

Q92597 Human, Q62433 Mouse, Q6JE36 Rat

Cellular Locus

Cytoplasm, cytosol, cytoskeleton, microtubule organizing center, centrosome, Nucleus, Cell membrane.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic phospho-peptide corresponding to residues surrounding Thr346 of human NDRG1 aa 321-370.

Isotype

IgG

Clone

PSH07-17

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell, FC, IF-Tissue

Positive Control

HT-29 treated with 100nM Calyculin A for 30 minutes cell lysate, HeLa cell lysate, HeLa serum starved for 4 hours then add 100nM insulin for 5 minutes cell lysate, C2C12 treated with 100nM insulin for 15 minutes cell lysate, HeLa serum starved for 24 hours then add 100nM Calyculin A for 30 minutes cell lysate, 293T, 293T treated with 100nM Calyculin A for 15 minutes cell lysate, C6 cell lysates, mouse kidney tissue, rat kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IHC-P: 1:2,000 ;IF-Cell: 1:100 ;FC: 1:1,000 ;IF-Tissue: 1:200-1:500

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 43 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

Frequently Asked Questions

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