GIC-20
Product Specifications
UNSPSC Description
GIC-20 is a dual inducer for apoptosis and ferroptosis. GIC-20 exhibits antitumor efficacy against fibrosarcoma[1].
Target Antigen
Apoptosis; Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gic-20.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(NCCCCCC(NC2=CC=C(N(C(C(NCCC3=CC=CC=C3)=O)C4=CC=CS4)C(CCl)=O)C=C2)=O)C(C5=CC=CC=C51)=O
Molecular Weight
697.24
References & Citations
[1]Ma F, et al., ML162 derivatives incorporating a naphthoquinone unit as ferroptosis/apoptosis inducers: Design, synthesis, anti-cancer activity, and drug-resistance reversal evaluation. Eur J Med Chem. 2024 Apr 15;270:116387.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162449/GIC-20-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162449/
Clinical Information
No Development Reported
CAS Number
2942242-60-4
Curated Selection
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