α-Glucosidase-IN-77
α-Glucosidase-IN-77 (Compound H7) is a non-competitive inhibitor for α-glucosidase with an IC50 of 1.25 μM. α-Glucosidase-IN-77 lowers blood glucose levels, improves glucose tolerance, regulates intestinal microbiota, and exhibits hepatoprotective effect in mouse type 2 diabetes model[1].
Product Specifications
UNSPSC
12352005
Target
Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/α-glucosidase-in-77.html
Smiles
O=C1C=C(OC2=C3CN(C(OC3=CC(O)=C12)=S)CC4=CC=C(C(F)(F)F)C=C4)C5=CC=C(C=C5)O
Molecular Formula
C25H16F3NO5S
Molecular Weight
499.46
References & Citations
[1]Liu H, et al., Apigenin analogs as α-glucosidase inhibitors: Molecular docking, biochemical, enzyme kinetic, and an in vivo mouse model study. Bioorg Chem. 2024 Dec;153:107956.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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