Deacetylsclerotiorin
Product Specifications
UNSPSC Description
Deacetylsclerotiorin is a secondary metabolite of chloramphenicol isolated from the fungus Bartalinia robillardoides strain LF550. Deacetylsclerotiorin has significant inhibitory effects on Candida albicans (IC50=24 μM), Trichophyton rubrum (IC50=2.83 μM) and Septoria tritici (IC50=7..45 μM). In addition, Deacetylsclerotiorin also exhibits inhibitory effects on the enzyme phosphodiesterase 4 (PDE4) (IC50=2.8 μM)[1].
Target Antigen
Fungal; Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/deacetylsclerotiorin.html
Smiles
O=C1[C@](O)(C(C2=COC(/C=C/C(C)=C/[C@H](CC)C)=CC2=C1Cl)=O)C
Molecular Weight
348.82
References & Citations
[1]Jansen, et al. "Helicusin E, isochromophilone X and isochromophilone XI: new chloroazaphilones produced by the fungus Bartalinia robillardoides strain LF550." Marine Drugs 11.3 (2013): 800-816.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126167/Deacetylsclerotiorin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126167/
Clinical Information
No Development Reported
CAS Number
34696-50-9
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS968677-01 0.02 mg (E-Coli)
Recombinant Chicken Guanine nucleotide-binding protein G (i) subunit alpha-2 (GNAI2)
Ask
View Details 
MBS968677-02 0.02 mg (Yeast)
Recombinant Chicken Guanine nucleotide-binding protein G (i) subunit alpha-2 (GNAI2)
Ask
View Details 
MBS968677-03 0.1 mg (E-Coli)
Recombinant Chicken Guanine nucleotide-binding protein G (i) subunit alpha-2 (GNAI2)
Ask
View Details MBS968677-04 0.1 mg (Yeast)
Recombinant Chicken Guanine nucleotide-binding protein G (i) subunit alpha-2 (GNAI2)
Ask
View Details MBS968677-05 0.02 mg (Baculovirus)
Recombinant Chicken Guanine nucleotide-binding protein G (i) subunit alpha-2 (GNAI2)
Ask
View Details MBS968677-06 0.02 mg (Mammalian-Cell)
Recombinant Chicken Guanine nucleotide-binding protein G (i) subunit alpha-2 (GNAI2)
Ask
View Details