Deacetylsclerotiorin
Deacetylsclerotiorin is a secondary metabolite of chloramphenicol isolated from the fungus Bartalinia robillardoides strain LF550. Deacetylsclerotiorin has significant inhibitory effects on Candida albicans (IC50=24 μM), Trichophyton rubrum (IC50=2.83 μM) and Septoria tritici (IC50=7..45 μM) . In addition, Deacetylsclerotiorin also exhibits inhibitory effects on the enzyme phosphodiesterase 4 (PDE4) (IC50=2.8 μM) [1].
Product Specifications
CAS Number
[34696-50-9]
UNSPSC
12352005
Target
Fungal; Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/deacetylsclerotiorin.html
Smiles
O=C1[C@](O)(C(C2=COC(/C=C/C(C)=C/[C@H](CC)C)=CC2=C1Cl)=O)C
Molecular Formula
C19H21ClO4
Molecular Weight
348.82
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE4
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