URAT1 inhibitor 11
URAT1 inhibitor 11 (Compound 7) is a URAT1 inhibitor with an IC50 value of 0.18 μM. URAT1 inhibitor 11 exhibits potent hypouricemic effects in hyperuricemic zebrafish induced by Potassium oxonate and Xanthine sodium salt (HY-W017389).
Product Specifications
CAS Number
2416416-13-0
UNSPSC
12352101
Target
URAT1
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/urat1-inhibitor-11.html
Smiles
OC(CCCN(C1=CC(F)=CC=C1)C2=CC=NC3=CC=C(C(F)(F)F)C=C32)=O
Molecular Formula
C20H16F4N2O2
Molecular Weight
392.35
References & Citations
[1]Hou X, et al. Identification of N-phenyl-N- (quinolin-4-yl) amino carboxylic acids as URAT1 inhibitors with hypouricemic effects. Bioorg Med Chem Lett. 2024 Dec 4;117:130053.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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