Isocyclosporin A

Isocyclosporin A is a degradation product of the immunosuppressant Cyclosporin A[1].

Product Specifications

CAS Number

[59865-16-6]

UNSPSC

12352005

Hazard Statement

H302, H350, H362

Target

Complement System; Cyclophilin; Drug Metabolite

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/isocyclosporin-a.html

Purity

99.05

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C/C=C/C[C@H]([C@]1([H])[C@@H](C(N[C@H](C(N(CC(N([C@H](C(N[C@H](C(N([C@H](C(N[C@H](C(N[C@@H](C(N([C@H](C(N([C@H](C(N([C@H](C(O1)=O)C(C)C)C)=O)CC(C)C)C)=O)CC(C)C)C)=O)C)=O)C)=O)CC(C)C)C)=O)C(C)C)=O)CC(C)C)C)=O)C)=O)CC)=O)NC)C

Molecular Formula

C62H111N11O12

Molecular Weight

1202.61

Precautions

H302, H350, H362

References & Citations

[1]Friis G J, Bundgaard H. Kinetics of degradation of cyclosporin A in acidic aqueous solution and its implication in its oral absorption[J]. International journal of pharmaceutics, 1992, 82 (1-2) : 79-83.