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CYB210010

Product Specifications

UNSPSC Description

CYB210010 is an orally bioavailable, long-acting serotonin 5-HT2 receptor agonist that selectively targets 5-HT2A and 5-HT2C receptors (EC50: 4.1 n, 7.3 nM). CYB210010 can enter the central nervous system, cause a head twitch response (HTR), and is not prone to behavioral tolerance during chronic administration[1].

Target Antigen

5-HT Receptor; Androgen Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein;Neuronal Signaling;Vitamin D Related/Nuclear Receptor

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cyb210010.html

Solubility

10 mM in DMSO

Smiles

COC1=C(CCN)C=C(OC)C(SC(F)(F)F)=C1.Cl

Molecular Weight

317.76

References & Citations

[1]Varty GB, et al. Synthesis and Structure-Activity Relationships of 2,5-Dimethoxy-4-Substituted Phenethylamines and the Discovery of CYB210010: A Potent, Orally Bioavailable and Long-Acting Serotonin 5-HT2 Receptor Agonist. J Med Chem. 2024 Apr 25;67(8):6144-6188.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-162423/CYB210010-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-162423/

Clinical Information

No Development Reported

CAS Number

2762568-47-6

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