GLP-1R agonist 21

GLP-1R agonist 21 (Compound I-134) is an agonist for glucagon-like peptide-1 receptor (GLP-1 receptor), with EC50 of 0.0104 nM[1].

Product Specifications

UNSPSC

12352005

Target

GLP Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/glp-1r-agonist-21.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC(F)=C(COC2=C(C(F)F)C=C(CCN(CC3=NC4=C(OC)C=C(C(O)=O)C=C4N3C[C@@H]5CCO5)[C@H]6C)C6=N2)C(F)=C1

Molecular Formula

C31H29ClF4N4O5

Molecular Weight

649.03

References & Citations

[1]Kitamura FY, et al., Fused ring compound having glp-1 receptor agonist effect. WO2024063143A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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