GLP-1R agonist 21
GLP-1R agonist 21 (Compound I-134) is an agonist for glucagon-like peptide-1 receptor (GLP-1 receptor), with EC50 of 0.0104 nM[1].
Product Specifications
UNSPSC
12352005
Target
GLP Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/glp-1r-agonist-21.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC(F)=C(COC2=C(C(F)F)C=C(CCN(CC3=NC4=C(OC)C=C(C(O)=O)C=C4N3C[C@@H]5CCO5)[C@H]6C)C6=N2)C(F)=C1
Molecular Formula
C31H29ClF4N4O5
Molecular Weight
649.03
References & Citations
[1]Kitamura FY, et al., Fused ring compound having glp-1 receptor agonist effect. WO2024063143A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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