Calnexin (Endoplasmic Reticulum Marker) (CANX/1543), 0.2mg/mL
Calnexin is a type-I integral membrane protein of the endoplasmic reticulum (ER) . It is a calcium-binding chaperone protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
CAS Number
9007-83-4
Synonyms
Calnexin; CANX; IP90; Major histocompatibility complex class I antigen-binding protein p88
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CANX
Gene ID
821
NCBI Gene ID
567968
UniProt
P27824
Swiss Prot
P27824
Host
Mouse
Species Reactivity
Human
Reactivity
Calnexin
Immunogen
Recombinant N-terminal fragment of human Calnexin protein (around aa 1-300) (exact sequence is proprietary)
Target Antigen
Calnexin
Clonality
Monoclonal
Clone
CANX/1543
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Chaperones, Immunology
Positive Control
HeLa, MCF-7 or U2OS cells. Kidney or small intestine.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
67 kDa (predicted) ; 80-90 kDa (observed)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA
Documents
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