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Anti-MRSA agent 20

Anti-MRSA agent 20 (Compound a4) is an anti-microbial agent (MIC: MRSA) . Anti-MRSA agent 20 binds to the ribosomal peptidyl transferase center and inhibits bacterial survival by inhibiting MRSA toxin synthesis and bacterial division. Anti-MRSA agent 20 significantly reduces the MRSA load in the lungs and attenuates lung injury in the MRSA-infected mice (ED50 = 6.48 mg/kg) [1].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/anti-mrsa-agent-20.html

Smiles

O=C(COC1=C(SCC(O[C@H]2[C@](C)([C@H](C)CC3)[C@]([H])(C(CC4)=O)[C@@]34[C@@H](C)[C@H](O)[C@](C)(C=C)C2)=O)C=CC=C1)N(CC5)CCS5(=O)=O

Molecular Formula

C34H47NO8S2

Molecular Weight

661.87

References & Citations

[1]Yi, et al. Design, synthesis, and biological evaluation of novel pleuromutilin derivatives with methicillin-resistant Staphylococcus aureus -targeting phenol linker groups. European journal of medicinal chemistry, 2025, 282, 117061.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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