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Anti-Mouse Notch4 Antibody (HMN4-14)

Anti-Mouse Notch4 Antibody (HMN4-14) is an anti-mouse Notch4 IgG monoclonal antibody. Anti-Mouse Notch4 Antibody (HMN4-14) reduces inflammation by restoring the expression of bispecific proteins. Anti-Mouse Notch4 Antibody (HMN4-14) can inhibit Th2/Th17 cell differentiation and improve Treg cell function. Anti-Mouse Notch4 Antibody (HMN4-14) can be used for research on inflammation conditions such as viral pneumonia and airway inflammation[1][2].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

Influenza Virus; Notch

Type

Inhibitory Antibodies

Related Pathways

Anti-infection; Neuronal Signaling; Stem Cell/Wnt

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-notch4-antibody-hmn4-14.html

Solubility

10 mM in DMSO

Smiles

[Anti-MouseNotch4Antibody(HMN4-14)]

Molecular Weight

(150 kDa)

References & Citations

[1]Harb H, et al. Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections. Immunity. 2021 Jun 8;54 (6) :1186-1199.e7.|[2]Xia M, et al. A Jagged 1-Notch 4 molecular switch mediates airway inflammation induced by ultrafine particles. J Allergy Clin Immunol. 2018 Oct;142 (4) :1243-1256.e17.

Shipping Conditions

Room temperature

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Frequently Asked Questions

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