JMV 179
JMV 179, a peptide closely related to CCK, is a cholecystokinin receptor (CKK) antagonist, with an IC50 of 30 nM[1][2].
Product Specifications
CAS Number
[119386-87-7]
UNSPSC
12352209
Target
Cholecystokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/jmv-179.html
Smiles
O=C(C[C@H](NC([C@@H](NC([C@H](NC(CNC([C@@H](NC([C@@H](NC(OC(C)(C)C)=O)CC1=CC=C(C=C1)OS(=O)(O)=O)=O)CCCC)=O)=O)CC2=CNC3=C2C=CC=C3)=O)CCCC)=O)C(OCCC4=CC=CC=C4)=O)O
Molecular Formula
C51H67N7O15S
Molecular Weight
1050.18
References & Citations
[1]K Kennedy, et al. Identification of two amino acids of the human cholecystokinin-A receptor that interact with the N-terminal moiety of cholecystokinin. J Biol Chem. 1997 Jan 31;272 (5) :2920-6.|[2]S Silvente Poirot, et al. Study of the states and populations of the rat pancreatic cholecystokinin receptor using the full peptide antagonist JMV 179. Eur J Biochem. 1993 Mar 1;212 (2) :529-38.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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