Obidoxime (dichloride)

Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated[1].

Product Specifications

CAS Number

[114-90-9]

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/obidoxime-dichloride.html

Purity

96.60

Solubility

DMSO : 1 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O/N=C/C1=CC=[N+](C=C1)COC[N+]2=CC=C(C=C2)/C=N/O.[Cl-].[Cl-]

Molecular Formula

C14H16Cl2N4O3

Molecular Weight

359.21

References & Citations

[1]Kassa J, et al. A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice.Toxicol Mech Methods. 2015 Mar;25 (3) :229-33.