PRRSV/CD163-IN-1

PRRSV/CD163-IN-1 is a PRRSV/CD163 inhibitor. PRRSV/CD163-IN-1 can inhibit the interaction between the PRRSV glycoprotein (GP2a or GP4) and the CD163-SRCR5 domain. PRRSV/CD163-IN-1 can be used for the research of porcine reproductive and respiratory syndrome (PRRS) [1].

Product Specifications

CAS Number

[560995-89-3]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Bacterial; Endogenous Metabolite

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/prrsv-cd163-in-1.html

Purity

98.28

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=S(NC1=NC2=C(N=C1NC3=CC=CC(S(=O)(N4CCOCC4)=O)=C3)C=CC=C2)(C5=CC=C(C=C5C)F)=O

Molecular Formula

C25H24FN5O5S2

Molecular Weight

557.62

Precautions

H315, H319, H335

References & Citations

[1]Chang Huang, et al. Small molecules block the interaction between porcine reproductive and respiratory syndrome virus and CD163 receptor and the infection of pig cells. Virol J. 2020 Jul 30;17 (1) :116