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RO3201195

RO3201195 (compound 1) is an inhibitor of p38 MAPK. RO3201195 inhibits WS cell proliferation with IC50 value of 190 nM[1].

Product Specifications

CAS Number

[249937-52-8]

UNSPSC

12352005

Target

P38 MAPK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ro3201195.html

Purity

99.77

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=CC(OCC(CO)O)=C1)C2=C(N(N=C2)C3=CC=C(C=C3)F)N

Molecular Formula

C19H18FN3O4

Molecular Weight

371.36

References & Citations

[1]Mark C. Bagley, et al. The effect of RO3201195 and a pyrazolyl ketone P38 MAPK inhibitor library on the proliferation of Werner syndrome cells. Org Biomol Chem. 2016, 14, 3.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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