Biotinylated Human TNFR2 / CD120b / TNFRSF1B Protein, Fc, Avitag™ (MALS verified)
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
Product Specifications
Background
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™) . The protein has a calculated MW of 53.3 kDa. The protein migrates as 65-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P20333-1
Expression Region
Leu 23 - Asp 257
Host
HEK293
Target
TNFR2
Conjugation
Biotin-labeled
Tag
C-Fc & C-Avi
Source
Human
Stability
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Immobilized Human TNF-alpha Protein, His Tag (Cat. No. TNA-H5228) at 5 μg/mL (100 μL/well) can bind Biotinylated Human TNFR2 Protein, Fc,Avitag (Cat. No. TN2-H82F3) with a linear range of 0.01-0.313 μg/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
53.3 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
25ug*1
Host or Source
HEK293
Species
Human
Protein ID
P20333-1
Preservative
Trehalose
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940149-500 1x 500 µL
CD106 / VCAM1 (1.4C3), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880965-100 1x 100 µL
MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (VU-11D1), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040178-100 1x 100 µL
CD50 (ICAM-3) (186-2G9), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940819-100 1x 100 µL
Caldesmon, HMW (h-Caldesmon) (h-CALD), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC942478-100 1x 100 µL
CD3e (T-Cell Marker) (C3e/2478), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details