EBOV-IN-5

EBOV-IN-5 (compound 14) is an antiviral agent that inhibits Ebola virus (EBOV) infection. EBOV-IN-5 inhibits the binding of the EBOV glycoprotein EBOV-GPcl to NPC1, an indispensable host receptor required for viral fusion/entry[1].

Product Specifications

CAS Number

[68207-15-8]

UNSPSC

12352005

Target

Filovirus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ebov-in-5.html

Solubility

10 mM in DMSO

Smiles

O=C(CN(CC)CC)NNC1=C(SC2=CC(Cl)=CC=C2[N+]([O-])=O)C=CC=C1

Molecular Formula

C18H21ClN4O3S

Molecular Weight

408.90

References & Citations

[1]Lasala F, et al. Identification of potential inhibitors of protein-protein interaction useful to fight against Ebola and other highly pathogenic viruses. Antiviral Res. 2021 Feb;186:105011.