RNF14, Human

The RNF14 protein is a critical E3 ubiquitin protein ligase that leads to activation of the RNF14-RNF25 translation quality control pathway during ribosome stalling. RNF14 is recruited by GCN1 to ubiquitinate and degrade translation factors, mainly EEF1A1/eEF1A, as well as ETF1/eRF1 and ribosomal proteins (RPL0, RPL1, RPL12, RPS13, RPS17) . RNF14 Protein, Human is the recombinant human-derived RNF14 protein, expressed by E. coli , with tag free.

Product Specifications

Product Name Alternative

RNF14 Protein, Human, Human, E. coli

UNSPSC

12352202

Type

Reference compound

Assay Protocol

https://www.medchemexpress.com/cytokines/rnf14-protein-human.html

Molecular Formula

9604 (Gene_ID) Q9UBS8 (S2-D474) (Accession)

Shipping Conditions

Dry ice.

Scientific Category

Recombinant Proteins

Curated Selection

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