(−) -Voacangarine
(−) -Voacangarine is an indole alkaloid, which exhibits cytotoxic effects against cancer cells HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 with IC50 of 5~20 mg/mL. (−) -Voacangarine inhibits the cultivation of Saccharomyces cerevisiae wildtype and repair-deficient mutants[1][2].
Product Specifications
CAS Number
545-84-6
UNSPSC
12352005
Target
Fungal
Type
Natural Products
Related Pathways
Anti-infection
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/voacangarine.html
Smiles
O=C([C@@]1([C@@]([C@@](C2)([H])[C@@H](O)C)([H])[N@@]3C[C@@]2([H])C1)C4=C(CC3)C5=CC(OC)=CC=C5N4)OC
Molecular Formula
C22H28N2O4
Molecular Weight
384.47
References & Citations
[1]Melo AA, et al., Cytostatic, cytotoxic and mutagenic effects of voacristine, an indole alkaloid in wild-type and repair-deficient yeasts. Mutat Res. 1986 Jul;171 (1) :17-24.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC402216-100 1x 100 µL
CD50 / ICAM3 (CG106), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC041081-100 1x 100 µL
CD45RO (190-2F2.5), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC471492-500 1x 500 µL
PAX8 (Renal Cell Marker) (PAX8/1492), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC041619-500 1x 500 µL
CD9 (TSPAN29) (Motility-Related Protein-1) (CD9/1619), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details