Anti-Lewis Y (Tumor Marker) (A70-C/C8)

This antibody recognizes a carbohydrate epitope common to the tumor-associated Lewis Y and Lewis b antigens (Fucalpha1-2Galbeta1-4/3GlcNAcbeta). Its specificity was established without doubt with a panel of 86 synthetic mono- and oligosaccharidic structures. Lewis Y is expressed in large bowel tumors and colorectal carcinomas. It may be useful in the classification of human renal and bladder tumors. The Lewis Y antigen has been evaluated as a clinical marker for the diagnosis and prognosis of cholangiocarcinoma, hepatocellular carcinoma and breast cancer.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Product Specifications

CAS Number

9007-83-4

Synonyms

Lewis Y antigen

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

Not Applicable

UniProt

Not Applicable

Cellular Locus

Cytoplasmic|Plasma membrane|Secreted (extracellular)

Host

Mouse

Species Reactivity

Human

Immunogen

Live Ls174T cells (human colon carcinoma cell line)

Target Antigen

Lewis-Y

Clonality

Monoclonal

Isotype

IgM

Clone

A70-C/C8

Conjugation

Purified, with BSA

Disease

Tumor

Source

Animal

Field of Research

Cancer

Positive Control

Lung, Colon, Bladder or Hepatocellular Carcinoma

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

Multiple

Additionnal Information

For coating for ELISA, order Ab without BSA|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry