S 17092
S 17092 (S 17092-1) is an orally active cerebral prolyl-endopeptidase (PEP) inhibitor with an IC50 of 1.2 nM. S 17092 inhibits cell apoptosis. S 17092 mechanism of action is to inhibit the activity of PEP, slowing down the degradation of neuroactive peptides and thus enhancing memory function. S 17092 can be used for the research of memory impairment and cognitive disorders associated with cerebral aging[1][2][3].
Product Specifications
CAS Number
176797-26-5
Product Name Alternative
S 17092-1
UNSPSC
12352005
Hazard Statement
H302
Target
Apoptosis; Prolyl Endopeptidase (PREP)
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s-17092.html
Concentration
10mM
Purity
99.78
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C([C@H]1[C@@](C2=CC=CC=C2)([H])C1)N3[C@]4([H])[C@](CCCC4)([H])C[C@H]3C(N5CCSC5)=O
Molecular Formula
C22H28N2O2S
Molecular Weight
384.53
Precautions
H302
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![IL2 Receptor beta (IL2RB) Mouse Monoclonal Antibody [Clone ID: OTI5A5]](https://cdn.genprice.uk/products/937/68dd18bb061270361e908d09/imageurl/cf812264.webp)
IL2 Receptor beta (IL2RB) Mouse Monoclonal Antibody [Clone ID: OTI5A5]
(3R,5R)-tert-Butyl 7-(2-(4-Chlorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate
![Bicyclo[3.2.1]octane-2,4-dione](https://cdn.genprice.uk/products/572/8605991554691/imageurl/trc-b529020-1g.webp)