Human Nectin-4 Protein, Fc Tag (MALS verified)
Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.
Product Specifications
Background
Specifications
Accession Number
Q96NY8-1
Expression Region
Gly 32 - Ser 349
Host
HEK293
Target
Nectin-4
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
Endotoxin
0.1 EU per μg
Purity
95%
Bioactivity
Immobilized Human Nectin-4, Fc Tag (Cat. No. NE4-H5255) at 1 μg/mL (100 μL/well) can bind Enfortumab with a linear range of 0.1-2 ng/mL (QC tested).
Format
Powder
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Additives
Trehalose
Molecular Weight
60.5 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*2
Host or Source
HEK293
Species
Human
Protein ID
Q96NY8-1
Preservative
Trehalose
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