Ambenoxan (hydrochloride)
Ambenoxan hydrochloride is a central nervous system-acting skeletal muscle relaxant that is effective in mice, rats, rabbits, dogs, and monkeys without loss of the righting reflex. It has no peripheral neuromuscular blocking effects and significantly reduces or eliminates decerebrate rigidity in rabbits, but does not antagonize the effects of strychnine, leptazol, or tremorine. Like other central nervous system depressants, ambenoxan prolongs sleep duration with hexobarbitone, but it has no local anesthetic effects. In anesthetized cats, the agent lowers blood pressure and reduces the pressor response to epinephrine, but has no effect on norepinephrine.
Product Specifications
CAS Number
[1617-99-8]
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ambenoxan-hydrochloride.html
Smiles
COCCOCCNCC1OC2=C(C=CC=C2)OC1.Cl
Molecular Formula
C14H22ClNO4
Molecular Weight
303.78
References & Citations
[1]The pharmacology of ambenoxan (2- (3 ',6 '-dioxaheptyl) - aminomethyl-1 : 4-benzodioxane), a centrally acting muscle relaxant
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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