Mouse GDNF / ATF Protein, His Tag (MALS verified)

Glial cell line-derived neurotrophic factor (GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta (TGF-beta) superfamily. It potently promotes the survival of of peripheral and central neurons. It signals through GFRα receptors, particularly GFRα1. Neuronal subpopulations that have been shown to be affected by GDNF include motoneurons, midbrain dopaminergic neurons, Purkinje cells and sympathetic neurons.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.0 kDa. The protein migrates as 16 kDa, 18 kDa and 22-24 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P48540

Expression Region

Ser 78 - Ile 211

Host

HEK293

Target

GDNF

Conjugation

Unconjugated

Tag

N-10xHis

Source

Mouse

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

0.1 EU per μg

Purity

90%

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

17.0 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Storage Conditions

-20°C

Package Size

50ug*1

Host or Source

HEK293

Species

Mouse

Protein ID

P48540

Preservative

Trehalose

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