Ca (II) -EDTA (disodium dihydrate)

CaII-EDTA disodium dihydrate (Calcium disodium EDTA dihydrate) is an orally active metal chelating reagent, exhibits bactericidal activities against periodontal pathogens Aggregatibacter actinomycetemcomitans, Prevotella intermedia and Porphyromonas gingivalis[1]. CaII-EDTA disodium dihydrate is effective chelating antidotes for lead-and cadmium poisoning[2][3].

Product Specifications

CAS Number

[6766-87-6]

Product Name Alternative

Calcium disodium EDTA (dihydrate)

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Bacterial

Type

Biochemical Assay Reagents

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Others

Assay Protocol

https://www.medchemexpress.com/ca-edta-disodium-dihydrate.html

Purity

99.9

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C1[O-][Ca+2]([N]2(C1)CC3=O)([O-]3)([O-]C4=O)([O-]5)[N](C4)(CC2)CC5=O.[2].[2].[Na+].O

Molecular Formula

C10H12CaN2O8.2H2O.2Na

Molecular Weight

410.30

Precautions

H302, H315, H319, H335

References & Citations

[1]Miura, T. et al., Ca (II) -EDTA shows antimicrobial activity against periodontopathic bacteria. Journal of Biomedical Science and Engineering, 5, 10-14.|[2]Saleh SM, et al., Do Nanoparticles of Calcium Disodium EDTA Minimize the Toxic Effects of Cadmium in Female Rats? Biol Trace Elem Res. 2023 Sep 18.|[3]Saxena G, et al., Lead-induced oxidative stress and hematological alterations and their response to combined administration of calcium disodium EDTA with a thiol chelator in rats. J Biochem Mol Toxicol. 2004;18 (4) :221-33.