Goat anti-ERBB2 Polyclonal antibody
Goat polyclonal antibody to ERBB2. This protein is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases containing a single transmembrane domain and has an approximate molecular weight of 185 kDa. ERBB2 contains no ligand binding domain and interacts with other EGF receptor family members to form a heterodimer, stabilize ligand binding, and enhance kinase-mediated downstream signalling. It has been shown to be involved in embryonic development and cancer progression.
Product Specifications
Specifications
Detects endogenous levels of ERBB2 by Western blot.
Product Name Alternative
CD340, erb-b2 receptor tyrosine kinase 2, HER2, HER-2, HER-2/neu, mLN 19, NEU, NGL and TKR1 antibody.
UNSPSC Description
Erb-b2 receptor tyrosine kinase
Volume
200 µL
Gene ID
ENSG00000141736
Accession Number
ENSG00000141736
Host
Goat
Antigen Species
Human
Reactivity
Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
Immunogen
Purified recombinant peptide derived from within residues 1,177 aa to the C-terminus of human ERBB2 produced in E. coli.
Target Antigen
Purified recombinant peptide derived from within residues 1,177 aa to the C-terminus of human ERBB2 produced in E. coli.
Immunogen Type
Recombinant protein
Target
Anti-ERBB2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Type
Primary
Sequence
MPHPPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPTAENPEYLGLDVPV
Applications
WB, IHC-P, IHC-F
Purification
Epitope affinity purified
Concentration
3 mg/mL
Dilution
WB:1:500-1:5,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000
Form
Buffer
PBS, 20% glycerol and 0.05% sodium azide
Storage Conditions
CAS Number
9007-83-4
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