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Goat anti-REP1 Polyclonal antibody

REP1 is the component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Mutations in this protein are a cause of a type of retinal degeneration, called choroideremia.

Product Specifications

Specifications

Detects endogenous Rep1 and in transfected cells by Western blot.

Product Name Alternative

CHM, choroideremia protein, DXS540, GGTA, HSD-32, RP1-93L7.1, rab escort protein 1, Rab geranylgeranyltransferase component A, REP-1, TCD antibody.

UNSPSC Description

Choroideremia (Rab escort protein 1)

Volume

200 µL

Gene ID

ENSG00000188419

Accession Number

ENSG00000188419

Host

Goat

Antigen Species

Human

Reactivity

Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other

Immunogen

Purified recombinant peptide derived from within residues 617 aa - stop at the C-terminus of human Rep1 produced in E. coli.

Target Antigen

Purified recombinant peptide derived from within residues 617 aa - stop at the C-terminus of human Rep1 produced in E. coli.

Immunogen Type

Recombinant protein

Target

Anti-REP1

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Type

Primary

Sequence

IIFDGDSLQPEASESSAIPEANSETFKESTNLGNLEESSE

Applications

WB

Purification

Epitope affinity purified

Concentration

4 mg/mL

Dilution

WB:1:500-1:2,000

Form

Polyclonal antibody supplied as a 200 or 500 µl (4 mg/mL) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.

Buffer

PBS, 20% glycerol and 0.05% sodium azide

Storage Conditions

For continuous use, store at 2-8 deg;C for one-two days. For extended storage, store in -20 deg;C freezer. Working dilution samples should be discarded if not used within 12 hours.

CAS Number

9007-83-4

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