Goat anti-REP1 Polyclonal antibody
REP1 is the component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Mutations in this protein are a cause of a type of retinal degeneration, called choroideremia.
Product Specifications
Specifications
Detects endogenous Rep1 and in transfected cells by Western blot.
Product Name Alternative
CHM, choroideremia protein, DXS540, GGTA, HSD-32, RP1-93L7.1, rab escort protein 1, Rab geranylgeranyltransferase component A, REP-1, TCD antibody.
UNSPSC Description
Choroideremia (Rab escort protein 1)
Volume
200 µL
Gene ID
ENSG00000188419
Accession Number
ENSG00000188419
Host
Goat
Antigen Species
Human
Reactivity
Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
Immunogen
Purified recombinant peptide derived from within residues 617 aa - stop at the C-terminus of human Rep1 produced in E. coli.
Target Antigen
Purified recombinant peptide derived from within residues 617 aa - stop at the C-terminus of human Rep1 produced in E. coli.
Immunogen Type
Recombinant protein
Target
Anti-REP1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Type
Primary
Sequence
IIFDGDSLQPEASESSAIPEANSETFKESTNLGNLEESSE
Applications
WB
Purification
Epitope affinity purified
Concentration
4 mg/mL
Dilution
WB:1:500-1:2,000
Form
Buffer
PBS, 20% glycerol and 0.05% sodium azide
Storage Conditions
CAS Number
9007-83-4
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