Goat anti-TLR2 ENS Polyclonal antibody

Goat polyclonal antibody to TLR2. It is a 84 kDa type I transmembrane glycoprotein and a member of TLR family. It contains many leucine-rich repeat sequences and the intracellular Toll Interleukin Receptor Domain. TLR2 forms heterodimer with TLR1 and TLR6. It is expressed in peripheral blood leukocytes, and highly expressed in monocytes in bone marrow, lymph nodes, and spleen. It is also detectable in other tissues. This protein recognizes molecular patterns of bacteria, fungi, protozoan pathogens and stimulates pro-inflammatory cytokines as part of innate immunity.

Product Specifications

CAS Number

9007-83-4

Specifications

Using liver, MDA-MD-435S and RAW264.7 cell lysates detects a band 85-90 kDa by Western blot.

Product Name Alternative

CD282, TIL4, toll/interleukin 1 receptor-like 4, toll/interleukin-1 receptor-like protein 4 antibody.

UNSPSC Description

Toll-like receptor 2

Volume

200 µL

Gene ID

ENSG00000137462

Accession Number

ENSG00000137462

Host

Goat

Antigen Species

Human

Reactivity

Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other

Immunogen

Purified recombinant peptide derived from within residues 736 aa to the C-terminus of human TLR2 produced in E. coli.

Target Antigen

Purified recombinant peptide derived from within residues 736 aa to the C-terminus of human TLR2 produced in E. coli.

Immunogen Type

Recombinant protein

Target

Anti-TLR2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Type

Primary

Sequence

LLEPIEKKAIPQRFCKLRKIMNTKTYLEWPMDEAQREGFWVNLRAAIKS

Applications

Purification

Epitope affinity purified

Concentration

3 mg/mL

Dilution

WB:1:500-1:2,000

Form

Polyclonal antibody supplied as a 200 µl (3 mg/mL) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.

Buffer

PBS, 20% glycerol and 0.05% sodium azide

Storage Conditions

For continuous use, store at 2-8 deg;C for one-two days. For extended storage, store in -20 deg;C freezer. Working dilution samples should be discarded if not used within 12 hours.