Goat anti-CD4 Polyclonal antibody
Goat polyclonal antibody to CD4. CD4 is a member of the immunoglobulin superfamily, a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and a receptor for the human immunodeficiency virus. This protein is expressed not only on the surface of T helper cells and regulatory T cells but also on monocytes, macrophages and dendritic cells. It functions to initiate or amplify the early phase of T-cell activation and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system.
Product Specifications
CAS Number
9007-83-4
Specifications
Using spleen lysate detects a 52 kDa band by Western blot.
Product Name Alternative
CD4mut, CD4 antigen (p55), CD4 Receptor, T-cell surface antigen T4/Leu-3 and T-cell surface glycoprotein CD4 antibody.
UNSPSC Description
CD4 molecule
Volume
200 µL
Gene ID
ENSG00000010610
Accession Number
ENSG00000010610
Host
Goat
Antigen Species
Human
Reactivity
Human, mouse, rat, bovine, canine, chicken/avian, donkey, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
Immunogen
Purified recombinant peptide derived from within 50 to 235 aa, corresponding to the external domain of human CD4 produced in E. coli.
Target Antigen
Purified recombinant peptide derived from within 50 to 235 aa, corresponding to the external domain of human CD4 produced in E. coli.
Immunogen Type
Recombinant protein
Target
Anti-CD4
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Type
Primary
Sequence
Applications
WB, IHC-P, IHC-F
Purification
Epitope affinity purified
Concentration
3 mg/mL
Dilution
WB:1:500-1:2,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000
Form
Buffer
PBS, 20% glycerol and 0.05% sodium azide
References & Citations
1. Helsby MA, Leader PM, Fenn JR, et al. BMC Cell Biol. 2014 Feb. PMID:24528853
Storage Conditions
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