Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Goat anti-Cathepsin D Polyclonal antibody

Goat polyclonal antibody to Cathepsin D. Cathepsin D is a lysosomal aspartic protease of the pepsin family. Acid protease active in intracellular protein breakdown. It is composed of a dimer of disulphide-linked heavy and light chains, both produced from a single protein precursor. It is involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Product Specifications

Specifications

This antibody gives a positive signal in the following human (Jurkat, HT1080, HUH, MDA-MB-231, ARPE19, SH-SY5Y), canine (MDCK) and monkey (COS-7) whole cell lysates.

Product Name Alternative

ceroid-lipofuscinosis, CLN10; CPSD, CTSD, lysosomal aspartyl protease, lysosomal aspartyl peptidase, neuronal 10 antibody.

UNSPSC Description

Cathepsin D

Volume

200 µL

Gene ID

ENSG00000117984

Accession Number

ENSG00000117984

Host

Goat

Antigen Species

Human

Reactivity

Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other

Immunogen

Purified recombinant peptide derived from within residues 275 aa to the C-terminus of human Cathepsin D produced in E. coli.

Target Antigen

Purified recombinant peptide derived from within residues 275 aa to the C-terminus of human Cathepsin D produced in E. coli.

Immunogen Type

Recombinant protein

Target

Anti-Cathepsin D

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Type

Primary

Sequence

DQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEAARL

Applications

WB, IF, IHC-P, IHC-F, IEM

Purification

Epitope affinity purified

Concentration

3 mg/mL

Dilution

WB:1:250-1:1,000, IF:1:50-1:200, IHC-P:1:200-1:1,000, IHC-F:1:200-1:1,000, IEM:1:50-1:200

Form

Polyclonal antibody supplied as a 200 or 500 µl (3 mg/mL) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.

Buffer

PBS, 20% glycerol and 0.05% sodium azide

References & Citations

1. Romagnoli M, Bresson L, Di-Cicco A, et al. Development 2020 Jan. PMID:31988184, 2. Pelkonen L, Sato K, Reinisalo M, et al. Mol Pharm 2017 Mar 6. PMID:28112518

Storage Conditions

For continuous use, store at 2-8 deg;C for one-two days. For extended storage, store in -20 deg;C freezer. Working dilution samples should be discarded if not used within 12 hours.

CAS Number

9007-83-4

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

prepro-Endothelin-1 (ET-1) (93-108) (Human)
023-41 200 μg

prepro-Endothelin-1 (ET-1) (93-108) (Human)

Ask
View Details
2-[4- (tert-Butoxycarbonyl) piperazin-1-yl]benzoic acid
OR0218 1 Pack

2-[4- (tert-Butoxycarbonyl) piperazin-1-yl]benzoic acid

Ask
View Details
HGF ORF Vector (Human) (pORF)
23234012 1.0 µg DNA

HGF ORF Vector (Human) (pORF)

Ask
View Details
SPDYE6 CRISPR Knock Out 293T Cell Line (Human)
45256141 1x10<sup>6</sup> cells/1.0ml

SPDYE6 CRISPR Knock Out 293T Cell Line (Human)

Ask
View Details
ALG11, CT (ALG11, GT8, GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Asparagine-linked glycosylation protein 11 homolog, Glycolipid 2-alpha-mannosyltransferase) (PE)
MBS6272904-01 0.2 mL

ALG11, CT (ALG11, GT8, GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Asparagine-linked glycosylation protein 11 homolog, Glycolipid 2-alpha-mannosyltransferase) (PE)

Ask
View Details
ALG11, CT (ALG11, GT8, GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Asparagine-linked glycosylation protein 11 homolog, Glycolipid 2-alpha-mannosyltransferase) (PE)
MBS6272904-02 5x 0.2 mL

ALG11, CT (ALG11, GT8, GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Asparagine-linked glycosylation protein 11 homolog, Glycolipid 2-alpha-mannosyltransferase) (PE)

Ask
View Details