Goat anti-ATXN3 Polyclonal antibody
Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder.
Product Specifications
CAS Number
9007-83-4
Specifications
Product Name Alternative
UNSPSC Description
Ataxin 3
Volume
500 µL
Gene ID
ENSG00000066427
Accession Number
ENSG00000066427
Host
Goat
Antigen Species
Human
Reactivity
Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
Immunogen
Purified recombinant peptide derived from within residues 120 aa to 250 aa of human ATXN3 produced in E. coli.
Target Antigen
Purified recombinant peptide derived from within residues 120 aa to 250 aa of human ATXN3 produced in E. coli.
Immunogen Type
Recombinant protein
Target
Anti-ATXN3
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Type
Primary
Sequence
KEHWFTVRKLGKQWFNLNSLLTGPELISDTYLALFLAQLQQEGYSIFVVKGDLPDCEADQLLQMIRVQQMHRPKLIGEELAQLKEQRVHKTDLERVLEANDGSGmLDEDEEDLQRALALSRQEIDMEDEEADL
Applications
WB
Purification
Epitope affinity purified
Concentration
3 mg/mL
Dilution
WB:1:250-1:2,000
Form
Buffer
PBS, 20% glycerol and 0.05% sodium azide
Storage Conditions
Frequently Asked Questions
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