L321
4-Methylphenoxyacetic acid-Oxindole-CF3 is the E3 ligase ligand part of L134. 4-Methylphenoxyacetic acid-Oxindole-CF3 can be utilized in PROTAC synthesis[1].
Product Specifications
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/l321.html
Smiles
CC1=CC=C(C(/C=C2C(NC3=C\2C=CC(C(F)(F)F)=C3)=O)=C1)OCC(OC(C)(C)C)=O
Molecular Formula
C23H22F3NO4
Molecular Weight
433.42
References & Citations
[1]Zhao M, et al. Design, Synthesis, and Activity Evaluation of BRD4 PROTAC Based on Alkenyl Oxindole-DCAF11 Pair. J Med Chem. 2024 Nov 14;67 (21) :19428-19447.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
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