MMP2-IN-4

MMP2-IN-4 (compound 3h) is a potent MMP2 inhibitor. MMP2-IN-4 inhibits MMP2, MMP9 and MMP12 with IC50s of 266.74, 402.75 and 1237.39 nM, respectively[1].

Product Specifications

CAS Number

[92535-43-8]

UNSPSC

12352005

Target

MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mmp2-in-4.html

Smiles

CC1=CC=C(S(N[C@@H](C(O)=O)CCC(NCC2=CC=CC=C2)=O)(=O)=O)C=C1

Molecular Formula

C19H22N2O5S

Molecular Weight

390.45

References & Citations

[1]Das S, et al. Derivatives of D (-) glutamine-based MMP-2 inhibitors as an effective remedy for the management of chronic myeloid leukemia-Part-I: Synthesis, biological screening and in silico binding interaction analysis. Eur J Med Chem. 2024 Aug 5;274:116563.