NCFP

NCFP is a metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulator (PAM) . NCFP can be used in the study of central nervous system diseases[1].

Product Specifications

CAS Number

[774548-65-1]

UNSPSC

12352005

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ncfp.html

Smiles

O=C(C1=NC=CC=C1)NC2=CC=C(Cl)C=C2CN(C(C3=C4C=CC=C3F)=O)C4=O

Molecular Formula

C21H13ClFN3O3

Molecular Weight

409.80

References & Citations

[1]Noetzel MJ, et al. A novel metabotropic glutamate receptor 5 positive allosteric modulator acts at a unique site and confers stimulus bias to mGlu5 signaling. Mol Pharmacol. 2013 Apr;83 (4) :835-47.