NCFP
Product Specifications
UNSPSC Description
NCFP is a metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulator (PAM). NCFP can be used in the study of central nervous system diseases[1].
Target Antigen
mGluR
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ncfp.html
Smiles
O=C(C1=NC=CC=C1)NC2=CC=C(Cl)C=C2CN(C(C3=C4C=CC=C3F)=O)C4=O
Molecular Weight
409.80
References & Citations
[1]Noetzel MJ, et al. A novel metabotropic glutamate receptor 5 positive allosteric modulator acts at a unique site and confers stimulus bias to mGlu5 signaling. Mol Pharmacol. 2013 Apr;83(4):835-47.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-123667/NCFP-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-123667/
Clinical Information
No Development Reported
CAS Number
774548-65-1
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