NCFP
NCFP is a metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulator (PAM) . NCFP can be used in the study of central nervous system diseases[1].
Product Specifications
CAS Number
774548-65-1
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ncfp.html
Smiles
O=C(C1=NC=CC=C1)NC2=CC=C(Cl)C=C2CN(C(C3=C4C=CC=C3F)=O)C4=O
Molecular Formula
C21H13ClFN3O3
Molecular Weight
409.80
References & Citations
[1]Noetzel MJ, et al. A novel metabotropic glutamate receptor 5 positive allosteric modulator acts at a unique site and confers stimulus bias to mGlu5 signaling. Mol Pharmacol. 2013 Apr;83 (4) :835-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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