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(Des-Bromo) -Neuropeptide B (1-23) (human)

(Des-Bromo) -Neuropeptide B (1-23) (human) is an orphan G-protein coupled receptor agonist with Kis of 1.2 nM and 341 nM for GPR7 (NPBW1) and GPR8 (NPBW2), respectively[1].

Product Specifications

CAS Number

[434897-64-0]

UNSPSC

12352209

Target

Neuropeptide B/W Receptor ; Orphan Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/des-bromo-neuropeptide-b-1-23-human.html

Solubility

H2O

Smiles

OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@@H](C)C(N[C@@H](C)C(NCC(N[C@H](C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CO)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](C)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(NCC(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)CC4=CN=CN4)=O)=O)=O)=O)=O)=O)NC([C@@H](N)CC5=CNC6=CC=CC=C56)=O

Molecular Formula

C107H162N30O30

Molecular Weight

2348.61

References & Citations

[1]Kanesaka M, et al. Development of a potent and selective GPR7 (NPBW1) agonist: a systematic structure-activity study of neuropeptide B. J Pept Sci. 2007 Jun;13 (6) :379-85.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

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