MD2 Recombinant Rabbit Monoclonal Antibody [PSH07-72]
Lymphocyte antigen 96, also known as "Myeloid Differentiation factor 2 (MD-2)," is a protein that in humans is encoded by the LY96 gene. The protein encoded by this gene is involved in binding lipopolysaccharide with Toll-Like Receptor (TLR4). The MD-2 protein appears to associate with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccharide (LPS), thus providing a link between the receptor and LPS signaling. That is, the primary interface between TLR4 and MD-2 is formed before binding LPS and the dimerization interface is induced by binding LPS.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
LY96, ESOP1, MD2
Swiss Prot
Q9Y6Y9 Human, Q9JHF9 Mouse
Cellular Locus
Secreted, extracellular space.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human MD2 aa 1-160.
Isotype
IgG
Clone
PSH07-72
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
U-87 MG cell lysate, Jurkat cell lysate, RAW264.7 cell lysate, C6 cell lysate, PC-12 cell lysate, Mouse kidney tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 18 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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