NOD-IN-1
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD) -like receptors, NOD1 and NOD2, with IC50 of 5.74 μM and 6.45 μM, respectively.
Product Specifications
CAS Number
[132819-92-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/NOD-IN-1.html
Purity
99.48
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(N1C(C(OCC)=O)=CC2=CC=CC=C21)(C3=CC=C(C)C=C3)=O
Molecular Formula
C18H17NO4S
Molecular Weight
343.40
Precautions
H302, H315, H319, H335
References & Citations
[1]Kecek Plesec K, et al. Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2. Bioorg Med Chem. 2016 Nov 1;24 (21) :5221-5234.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NOD1; NOD2
Available Sizes
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