SK-7041
SK-7041 is a HDAC inhibitor with the IC50 of 172 nM. SK-7041 induces the hyperacetylation of histones H3 and H4 .SK-7041 inhibits tumor cell growth in vivo and in vitro, induces cell apoptosis, and arrests cell cycle at the G1 phase[1].
Product Specifications
CAS Number
617690-98-9
UNSPSC
12352005
Target
Apoptosis; HDAC
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sk-7041.html
Smiles
ONC(/C=C/C(C=C1)=CC=C1CNC(C2=CC=C(C=C2)N(C)C)=O)=O
Molecular Formula
C19H21N3O3
Molecular Weight
339.39
References & Citations
[1]Park JH, et al. Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation. Clin Cancer Res. 2004;10 (15) :5271-5281.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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