BTF
BTF shows a selective binding affinity for OX1R with the Ki values of 2.33 nM and 62.8 nM of OX1R and OX2R, respectively[1].
Product Specifications
UNSPSC
12352101
Target
Orexin Receptor (OX Receptor)
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/btf.html
Smiles
O=C(C1=CC(F)=CC=C1N2N=CC=N2)N([C@H](C3)C)CCCN3C4=NC5=CC=CC=C5S4
Molecular Formula
C22H21FN6OS
Molecular Weight
436.51
References & Citations
[1]Ishizaka Y, et al. Structure-Affinity-Pharmacokinetics Relationships of Novel 18F-Labeled 1,4-Diazepane Derivatives for Orexin 1 Receptor Imaging. J Med Chem. Published online October 21, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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