YGZ-331
YGZ-331 is a sedative with a calming effect. YGZ-331 is a derivative of the adenosine nucleoside NGBA, which can increase GABA levels. YGZ-331 exerts a sedative-hypnotic effect by activating A1R and A2aR, and inhibiting CaMKII phosphorylation (pCaMKII) levels. YGZ-331 can reduce the spontaneous motor activity of mice[1].
Product Specifications
CAS Number
1350113-04-0
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ygz-331.html
Smiles
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N[C@H](C4=CC=CC=C4)CC)O1
Molecular Formula
C19H23N5O4
Molecular Weight
385.42
References & Citations
[1]Tang B, et al. The mechanism study of YZG-331 on sedative and hypnotic effects[J]. Behavioural Brain Research, 2022, 428: 113885.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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