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1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium)

2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium is an anionic phospholipid with oleic acid (18:1) and palmitic acid (16:0) tails containing a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposomes, and artificial membranes.

Product Specifications

CAS Number

321863-21-2

Product Name Alternative

1,2-POPS; 1,2-POPS; 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine (sodium) ; 1-Hexadecanoyl-2-- (9Z-octadecenoyl) -sn-glycero-3-phospho-L-serine (sodium salt)

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H331, H336, H351, H361, H372, H412

Target

Liposome

Type

Oligonucleotides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-l-serine-sodium.html

Purity

99.13

Solubility

DMSO : 2.22 mg/mL (ultrasonic; warming; adjust pH to 3 with 1 M HCL; heat to 60°C)

Smiles

OC([C@@H](N)COP(OC[C@@H](COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCC/C=C\CCCCCCCC)=O)(O[Na])=O)=O

Molecular Formula

C40H75NNaO10P

Molecular Weight

783.99

Precautions

H302, H315, H319, H331, H336, H351, H361, H372, H412

References & Citations

[1]Silin, V.I., and Hoogerheide, D.P. pH dependent electrical properties of the inner- and outer- leaflets of biomimetic cell membranes. J. Colloid Interface Sci. 594, 279-289 (2021) .|[2]Yu, M., Dorsey, K.H., Halseth, T., et al. Enhancement of anti-inflammatory effects of synthetic high-density lipoproteins by incorporation of anionic lipids. Mol. Pharm. 20 (11), 5454-5462 (2023) .

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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